Phenylpropanolamine (Proin) side effects in dogs
4,138 reports sent to the FDA between 1999 and 2026 involve Phenylpropanolamine in dogs. The most reported problems were vomiting, lethargy, loss of appetite. 38% were marked serious, and where it was recorded, signs eased after stopping the medicine in 80% of cases.
About this medicine
Phenylpropanolamine treats urinary incontinence.
Products with this ingredient include Proin. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Most reported side effects
Share = percentage of this medicine's reports that mention the problem. One report can list several problems.
Reports that it didn't work
Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.
How soon problems started
Time from the first dose to the first sign, where both dates were reported (2,672 reports).
How the animals did
Breeds named most often
Popular breeds appear more often because there are more of them.
- Labrador Retriever 460 reports
- German Shepherd Dog 201 reports
- Boxer (german Boxer) 124 reports
- Doberman Pinscher 104 reports
- Weimaraner 63 reports
- Australian Shepherd Dog 62 reports
- Golden Retriever 60 reports
- Siberian Husky 60 reports
- Yorkshire Terrier 59 reports
- Deutsche Dogge, Great Dane 56 reports