Levothyroxine side effects in dogs

3,012 reports sent to the FDA between 1998 and 2026 involve Levothyroxine in dogs. The most reported problems were vomiting, loss of appetite, lethargy. 44% were marked serious, and where it was recorded, signs eased after stopping the medicine in 93% of cases.

3,012Reports
44%Marked serious
18%Only medicine involved
35%Recovered
8.4%Died or euthanised
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

About this medicine

Levothyroxine treats an underactive thyroid.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

How soon problems started

Same day
225 12%
1–2 days
137 7.6%
3–7 days
141 7.8%
1–4 weeks
295 16%
Over a month
1,005 56%

Time from the first dose to the first sign, where both dates were reported (1,803 reports).

How the animals did

Recovered
981 33%
Recovered with lasting effects
87 2.9%
Still unwell when reported
821 27%
Died
87 2.9%
Euthanised
166 5.5%
Not known
870 29%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other hormone or endocrine medicines for dogs