Loss of appetite after Phenylpropanolamine (Proin) in dogs

524 reports to the FDA describe loss of appetite in dogs given Phenylpropanolamine. That is 13% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

524Reports
50%Marked serious
38%Recovered
18%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
118 33%
1–2 days
71 20%
3–7 days
35 9.9%
1–4 weeks
33 9.3%
Over a month
98 28%

How the animals did

Recovered
193 37%
Recovered with lasting effects
5 1.0%
Still unwell when reported
85 16%
Died
34 6.5%
Euthanised
61 12%
Not known
146 28%

Problems reported at the same time

Age of the animals

Under 1 year
6
1–3 years
62
4–7 years
91
8–11 years
165
12+ years
198

About this medicine

Phenylpropanolamine treats urinary incontinence.

Products with this ingredient include Proin. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Phenylpropanolamine cause loss of appetite in dogs?
524 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Phenylpropanolamine in dogs · Medicines most reported with loss of appetite