Kidney problems after Phenylpropanolamine (Proin) in dogs
The FDA has received 227 reports of kidney problems in dogs after Phenylpropanolamine. That is 5.5% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.
227Reports
77%Marked serious
10%Recovered
31%Died or euthanised
15 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Phenylpropanolamine treats urinary incontinence.
Products with this ingredient include Proin. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Phenylpropanolamine cause kidney problems in dogs?
- 227 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 15 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Kidney problems with similar medicines
- Kidney problems after Trilostane (Vetoryl) 1,689 reports · 14% of its reports
- Kidney problems after Insulin 232 reports · 3.2% of its reports
- Kidney problems after Levothyroxine 167 reports · 5.5% of its reports
All reported side effects of Phenylpropanolamine in dogs · Medicines most reported with kidney problems