Kidney problems after Insulin in dogs

The FDA has received 232 reports of kidney problems in dogs after Insulin. That is 3.2% of all reports for this medicine, compared with 2.4% across reports for all dog medicines.

232Reports

79%Marked serious

12%Recovered

30%Died or euthanised

21 daysTypical onset

How soon it started

Same day

18 16%

1–2 days

10 8.6%

3–7 days

13 11%

1–4 weeks

24 21%

Over a month

51 44%

How the animals did

Recovered

9 3.9%

Recovered with lasting effects

19 8.2%

Still unwell when reported

79 34%

Died

27 12%

Euthanised

43 19%

Not known

55 24%

Problems reported at the same time

Loss of appetite

97 42%

Didn't work as expected

96 41%

95 41%

80 34%

69 30%

65 28%

64 28%

40 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

103

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause kidney problems in dogs?: 232 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 21 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

Kidney problems after Trilostane (Vetoryl) 1,689 reports · 14% of its reports
Kidney problems after Phenylpropanolamine (Proin) 227 reports · 5.5% of its reports
Kidney problems after Levothyroxine 167 reports · 5.5% of its reports

All reported side effects of Insulin in dogs · Medicines most reported with kidney problems