Liver problems after Insulin in dogs

The FDA has received 417 reports of liver problems in dogs after Insulin. That is 5.7% of all reports for this medicine, compared with 4.6% across reports for all dog medicines.

417Reports

76%Marked serious

14%Recovered

21%Died or euthanised

36 daysTypical onset

How soon it started

Same day

29 14%

1–2 days

21 10%

3–7 days

20 9.9%

1–4 weeks

29 14%

Over a month

103 51%

How the animals did

Recovered

19 4.6%

Recovered with lasting effects

40 9.6%

Still unwell when reported

156 37%

Died

25 6.0%

Euthanised

61 15%

Not known

116 28%

Problems reported at the same time

Didn't work as expected

166 40%

140 34%

123 29%

106 25%

105 25%

95 23%

86 21%

65 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

227

12+ years

125

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause liver problems in dogs?: 417 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 36 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

Liver problems after Trilostane (Vetoryl) 2,663 reports · 22% of its reports
Liver problems after Phenylpropanolamine (Proin) 289 reports · 7.0% of its reports
Liver problems after Levothyroxine 319 reports · 11% of its reports

All reported side effects of Insulin in dogs · Medicines most reported with liver problems