Didn't prevent heartworm after Phenylpropanolamine (Proin) in dogs

23 reports to the FDA describe didn't prevent heartworm in dogs given Phenylpropanolamine. That is 0.6% of all reports for this medicine, compared with 13% across reports for all dog medicines, so it is reported less often than average with this medicine.

23Reports

13%Marked serious

13%Recovered

4.3%Died or euthanised

–Typical onset

How the animals did

Recovered

1 4.3%

Recovered with lasting effects

2 8.7%

Still unwell when reported

4 17%

Euthanised

1 4.3%

Not known

15 65%

Problems reported at the same time

Didn't work as expected

8 35%

Urinary incontinence

4 17%

Loss of appetite

2 8.7%

Drug dose omission

2 8.7%

Weight gain

2 8.7%

Diarrhea

2 8.7%

Vomiting

2 8.7%

Urinary tract disorder

1 4.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Phenylpropanolamine treats urinary incontinence.

Products with this ingredient include Proin. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Phenylpropanolamine cause didn't prevent heartworm in dogs?: 23 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't prevent heartworm with similar medicines

Didn't prevent heartworm after Levothyroxine 29 reports · 1.0% of its reports

All reported side effects of Phenylpropanolamine in dogs · Medicines most reported with didn't prevent heartworm