Polysulfated Glycosaminoglycan side effects in dogs

5,465 reports sent to the FDA between 1995 and 2026 involve Polysulfated Glycosaminoglycan in dogs. The most reported problems were vomiting, loss of appetite, diarrhea. 33% were marked serious, and where it was recorded, signs eased after stopping the medicine in 64% of cases.

5,465Reports
33%Marked serious
43%Only medicine involved
26%Recovered
11%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

1,566 29%
1,125 21%
1,037 19%
263 4.8%
247 4.5%
209 3.8%
196 3.6%
181 3.3%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't prevent heartworm
17 0.3%
Didn't stop worms
10 0.2%
Didn't stop fleas
6 0.1%
Didn't stop ticks
4 0.1%

How soon problems started

Same day
971 30%
1–2 days
294 9.1%
3–7 days
297 9.2%
1–4 weeks
506 16%
Over a month
1,167 36%

Time from the first dose to the first sign, where both dates were reported (3,235 reports).

How the animals did

Recovered
1,385 25%
Recovered with lasting effects
42 0.8%
Still unwell when reported
899 16%
Died
285 5.2%
Euthanised
301 5.5%
Not known
2,553 47%

Breeds named most often

Popular breeds appear more often because there are more of them.

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