Weight loss after Polysulfated Glycosaminoglycan in dogs

The FDA has received 247 reports of weight loss in dogs after Polysulfated Glycosaminoglycan. That is 4.5% of all reports for this medicine, compared with 1.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

247Reports
60%Marked serious
11%Recovered
19%Died or euthanised
32 daysTypical onset
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How soon it started

Same day
21 15%
1–2 days
9 6.4%
3–7 days
13 9.3%
1–4 weeks
26 19%
Over a month
71 51%

How the animals did

Recovered
23 9.3%
Recovered with lasting effects
5 2.0%
Still unwell when reported
80 32%
Died
13 5.3%
Euthanised
34 14%
Not known
92 37%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
3
4–7 years
36
8–11 years
88
12+ years
111

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause weight loss in dogs?
247 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 32 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Weight loss with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with weight loss