Diarrhea after Polysulfated Glycosaminoglycan in dogs

1,125 reports to the FDA describe diarrhea in dogs given Polysulfated Glycosaminoglycan. That is 21% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,125Reports
38%Marked serious
33%Recovered
10%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
235 33%
1–2 days
97 13%
3–7 days
78 11%
1–4 weeks
117 16%
Over a month
196 27%

How the animals did

Recovered
368 33%
Recovered with lasting effects
3 0.3%
Still unwell when reported
173 15%
Died
44 3.9%
Euthanised
70 6.2%
Not known
467 42%

Problems reported at the same time

Age of the animals

Under 1 year
3
1–3 years
68
4–7 years
188
8–11 years
444
12+ years
356

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause diarrhea in dogs?
1,125 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with diarrhea