Loss of appetite after Polysulfated Glycosaminoglycan in dogs

The FDA has received 1,132 reports of loss of appetite in dogs after Polysulfated Glycosaminoglycan. That is 21% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,132Reports
44%Marked serious
26%Recovered
18%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
207 30%
1–2 days
84 12%
3–7 days
69 10%
1–4 weeks
107 16%
Over a month
216 32%

How the animals did

Recovered
282 25%
Recovered with lasting effects
10 0.9%
Still unwell when reported
196 17%
Died
80 7.1%
Euthanised
125 11%
Not known
439 39%

Problems reported at the same time

533 47%
530 47%
355 31%
199 18%
110 9.7%

Age of the animals

Under 1 year
4
1–3 years
46
4–7 years
190
8–11 years
428
12+ years
439

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause loss of appetite in dogs?
1,132 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with loss of appetite