Breathing problems after Polysulfated Glycosaminoglycan in dogs

275 reports to the FDA describe breathing problems in dogs given Polysulfated Glycosaminoglycan. That is 5.0% of all reports for this medicine, compared with 2.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

275Reports

64%Marked serious

27%Recovered

32%Died or euthanised

8 daysTypical onset

How soon it started

Same day

55 32%

1–2 days

20 12%

3–7 days

10 5.9%

1–4 weeks

26 15%

Over a month

59 35%

How the animals did

Recovered

73 27%

Recovered with lasting effects

1 0.4%

Still unwell when reported

46 17%

Died

39 14%

Euthanised

50 18%

Not known

66 24%

Problems reported at the same time

105 38%

102 37%

87 32%

82 30%

56 20%

53 19%

50 18%

39 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

114

12+ years

112

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause breathing problems in dogs?: 275 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 8 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Breathing problems with similar medicines

Breathing problems after Melarsomine (Immiticide) 1,801 reports · 7.9% of its reports
Breathing problems after Diphenhydramine 574 reports · 12% of its reports
Breathing problems after Butorphanol 404 reports · 9.1% of its reports
Breathing problems after Cefpodoxime 198 reports · 4.9% of its reports
Breathing problems after Tramadol 375 reports · 10.0% of its reports
Breathing problems after Florfenicol + Mometasone + Terbinafine 163 reports · 4.6% of its reports
Breathing problems after Desoxycorticosterone Pivalate 135 reports · 4.0% of its reports
Breathing problems after Propofol 256 reports · 8.3% of its reports
Breathing problems after Dirlotapide 35 reports · 1.2% of its reports
Breathing problems after Isoflurane 266 reports · 9.6% of its reports

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with breathing problems