Weakness after Polysulfated Glycosaminoglycan in dogs

The FDA has received 263 reports of weakness in dogs after Polysulfated Glycosaminoglycan. That is 4.8% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

263Reports
62%Marked serious
15%Recovered
30%Died or euthanised
32 daysTypical onset
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How soon it started

Same day
37 21%
1–2 days
14 8.1%
3–7 days
9 5.2%
1–4 weeks
23 13%
Over a month
90 52%

How the animals did

Recovered
38 14%
Recovered with lasting effects
2 0.8%
Still unwell when reported
69 26%
Died
27 10%
Euthanised
52 20%
Not known
75 29%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
6
4–7 years
21
8–11 years
99
12+ years
130

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause weakness in dogs?
263 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 32 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Weakness with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with weakness