Weakness after Melarsomine (Immiticide) in dogs

The FDA has received 401 reports of weakness in dogs after Melarsomine. That is 1.8% of all reports for this medicine, compared with 1.4% across reports for all dog medicines.

401Reports
47%Marked serious
14%Recovered
12%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
79 34%
1–2 days
33 14%
3–7 days
31 13%
1–4 weeks
40 17%
Over a month
49 21%

How the animals did

Recovered
58 14%
Still unwell when reported
102 25%
Died
37 9.2%
Euthanised
11 2.7%
Not known
193 48%

Problems reported at the same time

Age of the animals

Under 1 year
3
1–3 years
158
4–7 years
145
8–11 years
63
12+ years
13

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause weakness in dogs?
401 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Weakness with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with weakness