Breathing problems after Melarsomine (Immiticide) in dogs

The FDA has received 1,801 reports of breathing problems in dogs after Melarsomine. That is 7.9% of all reports for this medicine, compared with 2.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,801Reports
53%Marked serious
16%Recovered
15%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
586 48%
1–2 days
102 8.4%
3–7 days
78 6.4%
1–4 weeks
177 15%
Over a month
276 23%

How the animals did

Recovered
292 16%
Recovered with lasting effects
3 0.2%
Still unwell when reported
451 25%
Died
218 12%
Euthanised
49 2.7%
Not known
788 44%

Problems reported at the same time

384 21%
361 20%
290 16%
260 14%
214 12%
203 11%

Age of the animals

Under 1 year
11
1–3 years
800
4–7 years
623
8–11 years
236
12+ years
51

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause breathing problems in dogs?
1,801 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Breathing problems with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with breathing problems