Loss of appetite after Melarsomine (Immiticide) in dogs

The FDA has received 1,950 reports of loss of appetite in dogs after Melarsomine. That is 8.6% of all reports for this medicine, compared with 8.4% across reports for all dog medicines.

1,950Reports
38%Marked serious
7.2%Recovered
12%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
282 28%
1–2 days
151 15%
3–7 days
124 12%
1–4 weeks
203 20%
Over a month
265 26%

How the animals did

Recovered
132 6.8%
Recovered with lasting effects
8 0.4%
Still unwell when reported
440 23%
Died
173 8.9%
Euthanised
59 3.0%
Not known
1,138 58%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
700
4–7 years
817
8–11 years
311
12+ years
54

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause loss of appetite in dogs?
1,950 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with loss of appetite