Melarsomine (Immiticide) side effects in dogs

22,672 reports sent to the FDA between 1995 and 2026 involve Melarsomine in dogs. The most reported problems were swelling, injection site reaction, vomiting. 41% were marked serious, and where it was recorded, signs eased after stopping the medicine in 22% of cases.

22,672Reports
41%Marked serious
70%Only medicine involved
11%Recovered
5.8%Died or euthanised
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About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Most reported side effects

3,470 15%
2,919 13%
2,412 11%
1,809 8.0%
1,315 5.8%
1,286 5.7%
1,170 5.2%
1,048 4.6%
937 4.1%
679 3.0%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop ticks
1 0.0%

How soon problems started

Same day
2,641 23%
1–2 days
868 7.6%
3–7 days
722 6.3%
1–4 weeks
2,097 18%
Over a month
5,139 45%

Time from the first dose to the first sign, where both dates were reported (11,467 reports).

How the animals did

Recovered
1,693 7.5%
Recovered with lasting effects
724 3.2%
Still unwell when reported
5,304 23%
Died
1,131 5.0%
Euthanised
180 0.8%
Not known
13,640 60%

Breeds named most often

Popular breeds appear more often because there are more of them.

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