Fever after Melarsomine (Immiticide) in dogs

The FDA has received 1,048 reports of fever in dogs after Melarsomine. That is 4.6% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,048Reports

32%Marked serious

6.8%Recovered

11%Died or euthanised

7 daysTypical onset

How soon it started

Same day

120 29%

1–2 days

49 12%

3–7 days

42 10%

1–4 weeks

98 24%

Over a month

99 24%

How the animals did

Recovered

70 6.7%

Recovered with lasting effects

1 0.1%

Still unwell when reported

177 17%

Died

88 8.4%

Euthanised

27 2.6%

Not known

685 65%

Problems reported at the same time

Lethargy

312 30%

Loss of appetite

301 29%

Swelling

223 21%

Injection site reaction

208 20%

203 19%

171 16%

133 13%

126 12%

Age of the animals

Under 1 year

1–3 years

400

4–7 years

409

8–11 years

138

12+ years

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause fever in dogs?: 1,048 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

Fever after Polysulfated Glycosaminoglycan 126 reports · 2.3% of its reports
Fever after Diphenhydramine 266 reports · 5.6% of its reports
Fever after Butorphanol 235 reports · 5.3% of its reports
Fever after Cefpodoxime 158 reports · 3.9% of its reports
Fever after Tramadol 137 reports · 3.6% of its reports
Fever after Florfenicol + Mometasone + Terbinafine 66 reports · 1.9% of its reports
Fever after Desoxycorticosterone Pivalate 73 reports · 2.2% of its reports
Fever after Propofol 141 reports · 4.6% of its reports
Fever after Dirlotapide 28 reports · 1.0% of its reports
Fever after Isoflurane 130 reports · 4.7% of its reports

All reported side effects of Melarsomine in dogs · Medicines most reported with fever