Injection site reaction after Melarsomine (Immiticide) in dogs

3,290 reports to the FDA describe injection site reaction in dogs given Melarsomine. That is 15% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

3,290Reports
34%Marked serious
6.5%Recovered
2.3%Died or euthanised
21 daysTypical onset
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How soon it started

Same day
500 25%
1–2 days
192 9.4%
3–7 days
95 4.7%
1–4 weeks
638 31%
Over a month
613 30%

How the animals did

Recovered
199 6.0%
Recovered with lasting effects
16 0.5%
Still unwell when reported
918 28%
Died
61 1.9%
Euthanised
16 0.5%
Not known
2,080 63%

Problems reported at the same time

987 30%
265 8.1%
211 6.4%
208 6.3%
144 4.4%
141 4.3%

Age of the animals

Under 1 year
27
1–3 years
1,646
4–7 years
1,052
8–11 years
315
12+ years
37

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause injection site reaction in dogs?
3,290 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 21 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with injection site reaction