Injection site reaction after Polysulfated Glycosaminoglycan in dogs

263 reports to the FDA describe injection site reaction in dogs given Polysulfated Glycosaminoglycan. That is 4.8% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

263Reports

29%Marked serious

21%Recovered

9.9%Died or euthanised

8 daysTypical onset

How soon it started

Same day

51 35%

1–2 days

7 4.8%

3–7 days

13 8.8%

1–4 weeks

26 18%

Over a month

50 34%

How the animals did

Recovered

56 21%

Still unwell when reported

39 15%

Died

10 3.8%

Euthanised

16 6.1%

Not known

142 54%

Problems reported at the same time

43 16%

42 16%

40 15%

32 12%

31 12%

26 9.9%

21 8.0%

20 7.6%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

107

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause injection site reaction in dogs?: 263 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 8 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

Injection site reaction after Melarsomine (Immiticide) 3,290 reports · 15% of its reports
Injection site reaction after Diphenhydramine 398 reports · 8.4% of its reports
Injection site reaction after Butorphanol 479 reports · 11% of its reports
Injection site reaction after Cefpodoxime 81 reports · 2.0% of its reports
Injection site reaction after Tramadol 123 reports · 3.3% of its reports
Injection site reaction after Desoxycorticosterone Pivalate 165 reports · 4.9% of its reports
Injection site reaction after Propofol 170 reports · 5.5% of its reports
Injection site reaction after Isoflurane 126 reports · 4.6% of its reports
Injection site reaction after Cephalexin 31 reports · 1.2% of its reports
Injection site reaction after Atipamezole 225 reports · 8.5% of its reports

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with injection site reaction