Swelling after Polysulfated Glycosaminoglycan in dogs

209 reports to the FDA describe swelling in dogs given Polysulfated Glycosaminoglycan. That is 3.8% of all reports for this medicine, compared with 2.8% across reports for all dog medicines.

209Reports
48%Marked serious
21%Recovered
20%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
37 34%
1–2 days
9 8.2%
3–7 days
12 11%
1–4 weeks
22 20%
Over a month
30 27%

How the animals did

Recovered
41 20%
Recovered with lasting effects
3 1.4%
Still unwell when reported
47 22%
Died
17 8.1%
Euthanised
24 11%
Not known
77 37%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
16
4–7 years
49
8–11 years
93
12+ years
45

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause swelling in dogs?
209 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with swelling