Death after Polysulfated Glycosaminoglycan in dogs

The FDA has received 567 reports of death in dogs after Polysulfated Glycosaminoglycan. That is 10% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

567Reports
80%Marked serious
0.7%Recovered
99%Died or euthanised
16 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
68 21%
1–2 days
28 8.5%
3–7 days
31 9.4%
1–4 weeks
75 23%
Over a month
128 39%

How the animals did

Recovered
4 0.7%
Died
259 46%
Euthanised
300 53%
Not known
4 0.7%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
10
4–7 years
52
8–11 years
211
12+ years
262

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause death in dogs?
567 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 16 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with death