Death after Isoflurane in dogs

The FDA has received 534 reports of death in dogs after Isoflurane. That is 19% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

534Reports
78%Marked serious
0.2%Recovered
99%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
197 53%
1–2 days
49 13%
3–7 days
58 16%
1–4 weeks
35 9.5%
Over a month
31 8.4%

How the animals did

Recovered
1 0.2%
Still unwell when reported
1 0.2%
Died
402 75%
Euthanised
127 24%
Not known
3 0.6%

Problems reported at the same time

Age of the animals

Under 1 year
105
1–3 years
86
4–7 years
130
8–11 years
128
12+ years
40

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause death in dogs?
534 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Isoflurane in dogs · Medicines most reported with death