Kidney problems after Isoflurane in dogs

The FDA has received 187 reports of kidney problems in dogs after Isoflurane. That is 6.8% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

187Reports
80%Marked serious
16%Recovered
38%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
26 16%
1–2 days
34 22%
3–7 days
52 33%
1–4 weeks
25 16%
Over a month
21 13%

How the animals did

Recovered
29 16%
Recovered with lasting effects
1 0.5%
Still unwell when reported
58 31%
Died
23 12%
Euthanised
48 26%
Not known
28 15%

Problems reported at the same time

Age of the animals

Under 1 year
19
1–3 years
43
4–7 years
62
8–11 years
49
12+ years
14

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause kidney problems in dogs?
187 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

All reported side effects of Isoflurane in dogs · Medicines most reported with kidney problems