Hyperphosphataemia after Isoflurane in dogs

The FDA has received 64 reports of hyperphosphataemia in dogs after Isoflurane. That is 2.3% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

64Reports
88%Marked serious
13%Recovered
55%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
5 9.1%
1–2 days
15 27%
3–7 days
19 35%
1–4 weeks
8 15%
Over a month
8 15%

How the animals did

Recovered
7 11%
Recovered with lasting effects
1 1.6%
Still unwell when reported
12 19%
Died
13 20%
Euthanised
22 34%
Not known
9 14%

Problems reported at the same time

Age of the animals

Under 1 year
9
1–3 years
13
4–7 years
24
8–11 years
12
12+ years
6

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause hyperphosphataemia in dogs?
64 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperphosphataemia with similar medicines

All reported side effects of Isoflurane in dogs · Medicines most reported with hyperphosphataemia