Hyperphosphataemia after Melarsomine (Immiticide) in dogs

139 reports to the FDA describe hyperphosphataemia in dogs given Melarsomine. That is 0.6% of all reports for this medicine, compared with 0.6% across reports for all dog medicines.

139Reports
56%Marked serious
7.9%Recovered
29%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
7 8.2%
1–2 days
10 12%
3–7 days
21 25%
1–4 weeks
23 27%
Over a month
24 28%

How the animals did

Recovered
10 7.2%
Recovered with lasting effects
1 0.7%
Still unwell when reported
37 27%
Died
29 21%
Euthanised
11 7.9%
Not known
51 37%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
53
4–7 years
55
8–11 years
25
12+ years
4

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause hyperphosphataemia in dogs?
139 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperphosphataemia with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with hyperphosphataemia