Liver problems after Isoflurane in dogs

237 reports to the FDA describe liver problems in dogs given Isoflurane. That is 8.6% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

237Reports
70%Marked serious
15%Recovered
34%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
39 19%
1–2 days
38 19%
3–7 days
60 30%
1–4 weeks
39 19%
Over a month
26 13%

How the animals did

Recovered
35 15%
Still unwell when reported
87 37%
Died
32 14%
Euthanised
49 21%
Not known
34 14%

Problems reported at the same time

Age of the animals

Under 1 year
16
1–3 years
40
4–7 years
79
8–11 years
78
12+ years
24

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause liver problems in dogs?
237 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Isoflurane in dogs · Medicines most reported with liver problems