Blood problems after Isoflurane in dogs

The FDA has received 101 reports of blood problems in dogs after Isoflurane. That is 3.7% of all reports for this medicine, compared with 1.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

101Reports

82%Marked serious

15%Recovered

43%Died or euthanised

3 daysTypical onset

How soon it started

Same day

24 28%

1–2 days

18 21%

3–7 days

15 17%

1–4 weeks

16 18%

Over a month

14 16%

How the animals did

Recovered

15 15%

Still unwell when reported

37 37%

Died

16 16%

Euthanised

27 27%

Not known

6 5.9%

Problems reported at the same time

54 53%

53 52%

50 50%

48 48%

44 44%

31 31%

29 29%

27 27%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause blood problems in dogs?: 101 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood problems with similar medicines

Blood problems after Melarsomine (Immiticide) 513 reports · 2.3% of its reports
Blood problems after Polysulfated Glycosaminoglycan 284 reports · 5.2% of its reports
Blood problems after Diphenhydramine 267 reports · 5.7% of its reports
Blood problems after Butorphanol 162 reports · 3.6% of its reports
Blood problems after Cefpodoxime 279 reports · 6.9% of its reports
Blood problems after Tramadol 236 reports · 6.3% of its reports
Blood problems after Florfenicol + Mometasone + Terbinafine 39 reports · 1.1% of its reports
Blood problems after Desoxycorticosterone Pivalate 187 reports · 5.6% of its reports
Blood problems after Propofol 106 reports · 3.5% of its reports
Blood problems after Dirlotapide 46 reports · 1.6% of its reports

All reported side effects of Isoflurane in dogs · Medicines most reported with blood problems