Lethargy after Isoflurane in dogs

The FDA has received 377 reports of lethargy in dogs after Isoflurane. That is 14% of all reports for this medicine, compared with 11% across reports for all dog medicines.

377Reports
70%Marked serious
24%Recovered
26%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
106 33%
1–2 days
81 25%
3–7 days
77 24%
1–4 weeks
35 11%
Over a month
27 8.3%

How the animals did

Recovered
83 22%
Recovered with lasting effects
7 1.9%
Still unwell when reported
126 33%
Died
50 13%
Euthanised
48 13%
Not known
63 17%

Problems reported at the same time

Age of the animals

Under 1 year
39
1–3 years
98
4–7 years
110
8–11 years
96
12+ years
27

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause lethargy in dogs?
377 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Isoflurane in dogs · Medicines most reported with lethargy