Lethargy after Desoxycorticosterone Pivalate in dogs

The FDA has received 630 reports of lethargy in dogs after Desoxycorticosterone Pivalate. That is 19% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

630Reports
48%Marked serious
19%Recovered
14%Died or euthanised
30 daysTypical onset
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How soon it started

Same day
20 9.3%
1–2 days
18 8.3%
3–7 days
16 7.4%
1–4 weeks
57 26%
Over a month
105 49%

How the animals did

Recovered
114 18%
Recovered with lasting effects
7 1.1%
Still unwell when reported
101 16%
Died
52 8.3%
Euthanised
35 5.6%
Not known
321 51%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
104
4–7 years
213
8–11 years
220
12+ years
76

About this medicine

Type: medicine.

Questions owners ask

Can Desoxycorticosterone Pivalate cause lethargy in dogs?
630 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 30 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Desoxycorticosterone Pivalate in dogs · Medicines most reported with lethargy