Excessive urination after Desoxycorticosterone Pivalate in dogs

The FDA has received 465 reports of excessive urination in dogs after Desoxycorticosterone Pivalate. That is 14% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

465Reports

42%Marked serious

9.5%Recovered

3.7%Died or euthanised

26 daysTypical onset

How soon it started

Same day

16 7.6%

1–2 days

17 8.1%

3–7 days

25 12%

1–4 weeks

62 29%

Over a month

91 43%

How the animals did

Recovered

42 9.0%

Recovered with lasting effects

2 0.4%

Still unwell when reported

96 21%

Died

12 2.6%

Euthanised

5 1.1%

Not known

308 66%

Problems reported at the same time

Excessive thirst

419 90%

High sodium-potassium ratio (na:k ratio)

123 26%

87 19%

71 15%

62 13%

59 13%

Decreased urine concentration

59 13%

Urinary incontinence

50 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

183

8–11 years

133

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Desoxycorticosterone Pivalate cause excessive urination in dogs?: 465 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 26 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive urination with similar medicines

Excessive urination after Melarsomine (Immiticide) 120 reports · 0.5% of its reports
Excessive urination after Polysulfated Glycosaminoglycan 121 reports · 2.2% of its reports
Excessive urination after Diphenhydramine 67 reports · 1.4% of its reports
Excessive urination after Butorphanol 57 reports · 1.3% of its reports
Excessive urination after Cefpodoxime 162 reports · 4.0% of its reports
Excessive urination after Tramadol 131 reports · 3.5% of its reports
Excessive urination after Florfenicol + Mometasone + Terbinafine 28 reports · 0.8% of its reports
Excessive urination after Propofol 26 reports · 0.8% of its reports
Excessive urination after Dirlotapide 54 reports · 1.9% of its reports
Excessive urination after Isoflurane 33 reports · 1.2% of its reports

All reported side effects of Desoxycorticosterone Pivalate in dogs · Medicines most reported with excessive urination