Excessive urination after Polysulfated Glycosaminoglycan in dogs

121 reports to the FDA describe excessive urination in dogs given Polysulfated Glycosaminoglycan. That is 2.2% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

121Reports

50%Marked serious

16%Recovered

11%Died or euthanised

36 daysTypical onset

How soon it started

Same day

10 15%

1–2 days

4 6.1%

3–7 days

7 11%

1–4 weeks

10 15%

Over a month

35 53%

How the animals did

Recovered

13 11%

Recovered with lasting effects

6 5.0%

Still unwell when reported

35 29%

Died

6 5.0%

Euthanised

7 5.8%

Not known

54 45%

Problems reported at the same time

95 79%

36 30%

35 29%

32 26%

28 23%

22 18%

19 16%

18 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause excessive urination in dogs?: 121 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 36 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive urination with similar medicines

Excessive urination after Melarsomine (Immiticide) 120 reports · 0.5% of its reports
Excessive urination after Diphenhydramine 67 reports · 1.4% of its reports
Excessive urination after Butorphanol 57 reports · 1.3% of its reports
Excessive urination after Cefpodoxime 162 reports · 4.0% of its reports
Excessive urination after Tramadol 131 reports · 3.5% of its reports
Excessive urination after Florfenicol + Mometasone + Terbinafine 28 reports · 0.8% of its reports
Excessive urination after Desoxycorticosterone Pivalate 465 reports · 14% of its reports
Excessive urination after Propofol 26 reports · 0.8% of its reports
Excessive urination after Dirlotapide 54 reports · 1.9% of its reports
Excessive urination after Isoflurane 33 reports · 1.2% of its reports

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with excessive urination