Excessive urination after Cefpodoxime in dogs

The FDA has received 162 reports of excessive urination in dogs after Cefpodoxime. That is 4.0% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

162Reports

45%Marked serious

9.3%Recovered

14%Died or euthanised

13 daysTypical onset

How soon it started

Same day

15 13%

1–2 days

14 12%

3–7 days

18 16%

1–4 weeks

30 26%

Over a month

37 32%

How the animals did

Recovered

15 9.3%

Still unwell when reported

79 49%

Died

11 6.8%

Euthanised

12 7.4%

Not known

45 28%

Problems reported at the same time

131 81%

48 30%

43 27%

39 24%

31 19%

29 18%

Urinary tract infection

29 18%

Weight loss

24 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Cefpodoxime cause excessive urination in dogs?: 162 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive urination with similar medicines

Excessive urination after Melarsomine (Immiticide) 120 reports · 0.5% of its reports
Excessive urination after Polysulfated Glycosaminoglycan 121 reports · 2.2% of its reports
Excessive urination after Diphenhydramine 67 reports · 1.4% of its reports
Excessive urination after Butorphanol 57 reports · 1.3% of its reports
Excessive urination after Tramadol 131 reports · 3.5% of its reports
Excessive urination after Florfenicol + Mometasone + Terbinafine 28 reports · 0.8% of its reports
Excessive urination after Desoxycorticosterone Pivalate 465 reports · 14% of its reports
Excessive urination after Propofol 26 reports · 0.8% of its reports
Excessive urination after Dirlotapide 54 reports · 1.9% of its reports
Excessive urination after Isoflurane 33 reports · 1.2% of its reports

All reported side effects of Cefpodoxime in dogs · Medicines most reported with excessive urination