Lethargy after Cefpodoxime in dogs

The FDA has received 737 reports of lethargy in dogs after Cefpodoxime. That is 18% of all reports for this medicine, compared with 11% across reports for all dog medicines, so it is reported unusually often with this medicine.

737Reports
44%Marked serious
17%Recovered
21%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
99 19%
1–2 days
89 17%
3–7 days
107 20%
1–4 weeks
115 22%
Over a month
115 22%

How the animals did

Recovered
118 16%
Recovered with lasting effects
9 1.2%
Still unwell when reported
259 35%
Died
83 11%
Euthanised
69 9.4%
Not known
199 27%

Problems reported at the same time

Age of the animals

Under 1 year
46
1–3 years
120
4–7 years
254
8–11 years
227
12+ years
85

About this medicine

Type: medicine.

Questions owners ask

Can Cefpodoxime cause lethargy in dogs?
737 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Cefpodoxime in dogs · Medicines most reported with lethargy