Lethargy after Propofol in dogs

The FDA has received 315 reports of lethargy in dogs after Propofol. That is 10% of all reports for this medicine, compared with 11% across reports for all dog medicines.

315Reports
72%Marked serious
18%Recovered
29%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
72 27%
1–2 days
82 31%
3–7 days
49 19%
1–4 weeks
38 15%
Over a month
21 8.0%

How the animals did

Recovered
55 17%
Recovered with lasting effects
1 0.3%
Still unwell when reported
99 31%
Died
46 15%
Euthanised
46 15%
Not known
68 22%

Problems reported at the same time

Age of the animals

Under 1 year
24
1–3 years
88
4–7 years
88
8–11 years
85
12+ years
24

About this medicine

Type: medicine.

Questions owners ask

Can Propofol cause lethargy in dogs?
315 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

All reported side effects of Propofol in dogs · Medicines most reported with lethargy