Liver problems after Propofol in dogs

The FDA has received 201 reports of liver problems in dogs after Propofol. That is 6.5% of all reports for this medicine, compared with 4.6% across reports for all dog medicines.

201Reports
77%Marked serious
10%Recovered
37%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
33 19%
1–2 days
45 26%
3–7 days
36 21%
1–4 weeks
36 21%
Over a month
20 12%

How the animals did

Recovered
20 10.0%
Recovered with lasting effects
1 0.5%
Still unwell when reported
73 36%
Died
29 14%
Euthanised
46 23%
Not known
32 16%

Problems reported at the same time

Age of the animals

Under 1 year
7
1–3 years
42
4–7 years
66
8–11 years
62
12+ years
24

About this medicine

Type: medicine.

Questions owners ask

Can Propofol cause liver problems in dogs?
201 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Propofol in dogs · Medicines most reported with liver problems