Liver problems after Diphenhydramine in dogs
500 reports to the FDA describe liver problems in dogs given Diphenhydramine. That is 11% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.
500Reports
77%Marked serious
13%Recovered
26%Died or euthanised
1 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Type: medicine.
Questions owners ask
- Can Diphenhydramine cause liver problems in dogs?
- 500 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 1 day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Liver problems with similar medicines
- Liver problems after Melarsomine (Immiticide) 1,315 reports · 5.8% of its reports
- Liver problems after Polysulfated Glycosaminoglycan 548 reports · 10% of its reports
- Liver problems after Butorphanol 371 reports · 8.4% of its reports
- Liver problems after Cefpodoxime 475 reports · 12% of its reports
- Liver problems after Tramadol 684 reports · 18% of its reports
- Liver problems after Florfenicol + Mometasone + Terbinafine 133 reports · 3.8% of its reports
- Liver problems after Desoxycorticosterone Pivalate 276 reports · 8.3% of its reports
- Liver problems after Propofol 201 reports · 6.5% of its reports
- Liver problems after Dirlotapide 284 reports · 10% of its reports
- Liver problems after Isoflurane 237 reports · 8.6% of its reports
All reported side effects of Diphenhydramine in dogs · Medicines most reported with liver problems