Liver problems after Butorphanol in dogs

371 reports to the FDA describe liver problems in dogs given Butorphanol. That is 8.4% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

371Reports
63%Marked serious
11%Recovered
30%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
63 23%
1–2 days
49 18%
3–7 days
57 21%
1–4 weeks
56 20%
Over a month
49 18%

How the animals did

Recovered
39 11%
Recovered with lasting effects
3 0.8%
Still unwell when reported
137 37%
Died
49 13%
Euthanised
64 17%
Not known
79 21%

Problems reported at the same time

Age of the animals

Under 1 year
17
1–3 years
58
4–7 years
101
8–11 years
141
12+ years
51

About this medicine

Type: medicine.

Questions owners ask

Can Butorphanol cause liver problems in dogs?
371 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Butorphanol in dogs · Medicines most reported with liver problems