Liver problems after Florfenicol + Mometasone + Terbinafine in dogs

The FDA has received 133 reports of liver problems in dogs after Florfenicol + Mometasone + Terbinafine. That is 3.8% of all reports for this medicine, compared with 4.6% across reports for all dog medicines.

133Reports
72%Marked serious
11%Recovered
20%Died or euthanised
10 daysTypical onset
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How soon it started

Same day
28 25%
1–2 days
12 11%
3–7 days
13 12%
1–4 weeks
28 25%
Over a month
29 26%

How the animals did

Recovered
10 7.5%
Recovered with lasting effects
4 3.0%
Still unwell when reported
43 32%
Died
7 5.3%
Euthanised
20 15%
Not known
49 37%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
15
4–7 years
40
8–11 years
42
12+ years
25

About this medicine

Type: medicine.

Questions owners ask

Can Florfenicol + Mometasone + Terbinafine cause liver problems in dogs?
133 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 10 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Florfenicol + Mometasone + Terbinafine in dogs · Medicines most reported with liver problems