Wobbliness (ataxia) after Florfenicol + Mometasone + Terbinafine in dogs

The FDA has received 430 reports of wobbliness (ataxia) in dogs after Florfenicol + Mometasone + Terbinafine. That is 12% of all reports for this medicine, compared with 2.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

430Reports

71%Marked serious

20%Recovered

8.8%Died or euthanised

Same dayTypical onset

How soon it started

Same day

201 52%

1–2 days

80 21%

3–7 days

34 8.7%

1–4 weeks

39 10%

Over a month

35 9.0%

How the animals did

Recovered

82 19%

Recovered with lasting effects

6 1.4%

Still unwell when reported

122 28%

Died

8 1.9%

Euthanised

30 7.0%

Not known

182 42%

Problems reported at the same time

Head tilt - ear disorder

160 37%

150 35%

132 31%

118 27%

89 21%

85 20%

63 15%

49 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

115

8–11 years

119

12+ years

104

About this medicine

Type: medicine.

Questions owners ask

Can Florfenicol + Mometasone + Terbinafine cause wobbliness (ataxia) in dogs?: 430 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Wobbliness (ataxia) with similar medicines

Wobbliness (ataxia) after Melarsomine (Immiticide) 599 reports · 2.6% of its reports
Wobbliness (ataxia) after Polysulfated Glycosaminoglycan 150 reports · 2.7% of its reports
Wobbliness (ataxia) after Diphenhydramine 169 reports · 3.6% of its reports
Wobbliness (ataxia) after Butorphanol 125 reports · 2.8% of its reports
Wobbliness (ataxia) after Cefpodoxime 182 reports · 4.5% of its reports
Wobbliness (ataxia) after Tramadol 168 reports · 4.5% of its reports
Wobbliness (ataxia) after Desoxycorticosterone Pivalate 33 reports · 1.0% of its reports
Wobbliness (ataxia) after Propofol 69 reports · 2.2% of its reports
Wobbliness (ataxia) after Dirlotapide 23 reports · 0.8% of its reports
Wobbliness (ataxia) after Isoflurane 81 reports · 2.9% of its reports

All reported side effects of Florfenicol + Mometasone + Terbinafine in dogs · Medicines most reported with wobbliness (ataxia)