Ocular discharge after Florfenicol + Mometasone + Terbinafine in dogs

The FDA has received 216 reports of ocular discharge in dogs after Florfenicol + Mometasone + Terbinafine. That is 6.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

216Reports

80%Marked serious

19%Recovered

6.5%Died or euthanised

1 daysTypical onset

How soon it started

Same day

73 40%

1–2 days

43 24%

3–7 days

16 8.8%

1–4 weeks

31 17%

Over a month

18 9.9%

How the animals did

Recovered

37 17%

Recovered with lasting effects

3 1.4%

Still unwell when reported

82 38%

Died

2 0.9%

Euthanised

12 5.6%

Not known

80 37%

Problems reported at the same time

Corneal ulcer

110 51%

Squinting

77 36%

Schirmer tear test

76 35%

Keratoconjunctivitis sicca

74 34%

57 26%

55 25%

55 25%

54 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Florfenicol + Mometasone + Terbinafine cause ocular discharge in dogs?: 216 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Ocular discharge with similar medicines

Ocular discharge after Melarsomine (Immiticide) 23 reports · 0.1% of its reports
Ocular discharge after Diphenhydramine 52 reports · 1.1% of its reports
Ocular discharge after Cefpodoxime 32 reports · 0.8% of its reports
Ocular discharge after Cephalexin 22 reports · 0.8% of its reports
Ocular discharge after Clotrimazole + Gentamicin + Mometasone 21 reports · 0.8% of its reports
Ocular discharge after Betamethasone + Florfenicol + Terbinafine 46 reports · 1.9% of its reports
Ocular discharge after Ketoconazole 66 reports · 2.9% of its reports
Ocular discharge after Etodolac 25 reports · 1.3% of its reports
Ocular discharge after Neomycin 23 reports · 5.2% of its reports
Ocular discharge after Neomycin + Polymyxin B 26 reports · 13% of its reports

All reported side effects of Florfenicol + Mometasone + Terbinafine in dogs · Medicines most reported with ocular discharge