Keratoconjunctivitis sicca after Florfenicol + Mometasone + Terbinafine in dogs

175 reports to the FDA describe keratoconjunctivitis sicca in dogs given Florfenicol + Mometasone + Terbinafine. That is 4.9% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

175Reports
85%Marked serious
22%Recovered
4.0%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
65 44%
1–2 days
32 22%
3–7 days
16 11%
1–4 weeks
18 12%
Over a month
16 11%

How the animals did

Recovered
34 19%
Recovered with lasting effects
5 2.9%
Still unwell when reported
63 36%
Euthanised
7 4.0%
Not known
66 38%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
30
4–7 years
53
8–11 years
53
12+ years
32

About this medicine

Type: medicine.

Questions owners ask

Can Florfenicol + Mometasone + Terbinafine cause keratoconjunctivitis sicca in dogs?
175 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Keratoconjunctivitis sicca with similar medicines

All reported side effects of Florfenicol + Mometasone + Terbinafine in dogs · Medicines most reported with keratoconjunctivitis sicca