Keratoconjunctivitis sicca after Ormetoprim + Sulfadimethoxine in dogs

41 reports to the FDA describe keratoconjunctivitis sicca in dogs given Ormetoprim + Sulfadimethoxine. That is 4.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

41Reports
9.8%Marked serious
2.4%Recovered
7.3%Died or euthanised
–Typical onset
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How the animals did

Recovered
1 2.4%
Still unwell when reported
6 15%
Died
1 2.4%
Euthanised
2 4.9%
Not known
31 76%

Problems reported at the same time

6 15%
Ocular discharge
6 15%
Conjunctivitis
6 15%
Corneal ulcer
5 12%

Age of the animals

Under 1 year
2
1–3 years
12
4–7 years
15
8–11 years
8
12+ years
2

About this medicine

Type: medicine.

Questions owners ask

Can Ormetoprim + Sulfadimethoxine cause keratoconjunctivitis sicca in dogs?
41 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Keratoconjunctivitis sicca with similar medicines

All reported side effects of Ormetoprim + Sulfadimethoxine in dogs · Medicines most reported with keratoconjunctivitis sicca