Keratoconjunctivitis sicca after Neomycin in dogs

The FDA has received 25 reports of keratoconjunctivitis sicca in dogs after Neomycin. That is 5.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

25Reports
92%Marked serious
36%Recovered
0.0%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
14 61%
1–2 days
4 17%
3–7 days
0 0.0%
1–4 weeks
3 13%
Over a month
2 8.7%

How the animals did

Recovered
8 32%
Recovered with lasting effects
1 4.0%
Still unwell when reported
4 16%
Not known
12 48%

Problems reported at the same time

Schirmer tear test
14 56%
Dry nose
12 48%
Squinting
11 44%
Blepharospasm
11 44%
10 40%

Age of the animals

Under 1 year
0
1–3 years
5
4–7 years
10
8–11 years
9
12+ years
1

About this medicine

Type: medicine.

Questions owners ask

Can Neomycin cause keratoconjunctivitis sicca in dogs?
25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Keratoconjunctivitis sicca with similar medicines

All reported side effects of Neomycin in dogs · Medicines most reported with keratoconjunctivitis sicca