Fever after Ormetoprim + Sulfadimethoxine in dogs

The FDA has received 96 reports of fever in dogs after Ormetoprim + Sulfadimethoxine. That is 11% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

96Reports
5.2%Marked serious
1.0%Recovered
14%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
4 27%
1–2 days
1 6.7%
3–7 days
3 20%
1–4 weeks
6 40%
Over a month
1 6.7%

How the animals did

Recovered
1 1.0%
Still unwell when reported
13 14%
Died
12 13%
Euthanised
1 1.0%
Not known
69 72%

Problems reported at the same time

Age of the animals

Under 1 year
9
1–3 years
33
4–7 years
30
8–11 years
18
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Ormetoprim + Sulfadimethoxine cause fever in dogs?
96 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

All reported side effects of Ormetoprim + Sulfadimethoxine in dogs · Medicines most reported with fever