Blepharospasm after Florfenicol + Mometasone + Terbinafine in dogs

The FDA has received 91 reports of blepharospasm in dogs after Florfenicol + Mometasone + Terbinafine. That is 2.6% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

91Reports

88%Marked serious

24%Recovered

4.4%Died or euthanised

Same dayTypical onset

How soon it started

Same day

42 53%

1–2 days

13 16%

3–7 days

7 8.9%

1–4 weeks

6 7.6%

Over a month

11 14%

How the animals did

Recovered

21 23%

Recovered with lasting effects

1 1.1%

Still unwell when reported

27 30%

Euthanised

4 4.4%

Not known

38 42%

Problems reported at the same time

Corneal ulcer

64 70%

Ocular discharge

48 53%

Keratoconjunctivitis sicca

41 45%

33 36%

27 30%

27 30%

26 29%

25 27%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Florfenicol + Mometasone + Terbinafine cause blepharospasm in dogs?: 91 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blepharospasm with similar medicines

Blepharospasm after Ketoconazole 21 reports · 0.9% of its reports
Blepharospasm after Pilocarpine 20 reports · 26% of its reports

All reported side effects of Florfenicol + Mometasone + Terbinafine in dogs · Medicines most reported with blepharospasm