Death after Diphenhydramine in dogs
455 reports to the FDA describe death in dogs given Diphenhydramine. That is 9.6% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.
455Reports
99%Marked serious
0.0%Recovered
100%Died or euthanised
1 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Type: medicine.
Questions owners ask
- Can Diphenhydramine cause death in dogs?
- 455 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 1 day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Death with similar medicines
- Death after Melarsomine (Immiticide) 1,270 reports · 5.6% of its reports
- Death after Polysulfated Glycosaminoglycan 567 reports · 10% of its reports
- Death after Butorphanol 718 reports · 16% of its reports
- Death after Cefpodoxime 427 reports · 11% of its reports
- Death after Tramadol 636 reports · 17% of its reports
- Death after Florfenicol + Mometasone + Terbinafine 160 reports · 4.5% of its reports
- Death after Desoxycorticosterone Pivalate 289 reports · 8.7% of its reports
- Death after Propofol 637 reports · 21% of its reports
- Death after Dirlotapide 126 reports · 4.5% of its reports
- Death after Isoflurane 534 reports · 19% of its reports
All reported side effects of Diphenhydramine in dogs · Medicines most reported with death