Excessive urination after Tramadol in dogs

The FDA has received 131 reports of excessive urination in dogs after Tramadol. That is 3.5% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

131Reports

64%Marked serious

18%Recovered

19%Died or euthanised

13 daysTypical onset

How soon it started

Same day

14 13%

1–2 days

14 13%

3–7 days

15 14%

1–4 weeks

27 26%

Over a month

35 33%

How the animals did

Recovered

19 15%

Recovered with lasting effects

4 3.1%

Still unwell when reported

69 53%

Died

5 3.8%

Euthanised

20 15%

Not known

14 11%

Problems reported at the same time

108 82%

50 38%

48 37%

46 35%

45 34%

39 30%

30 23%

25 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Tramadol cause excessive urination in dogs?: 131 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive urination with similar medicines

Excessive urination after Melarsomine (Immiticide) 120 reports · 0.5% of its reports
Excessive urination after Polysulfated Glycosaminoglycan 121 reports · 2.2% of its reports
Excessive urination after Diphenhydramine 67 reports · 1.4% of its reports
Excessive urination after Butorphanol 57 reports · 1.3% of its reports
Excessive urination after Cefpodoxime 162 reports · 4.0% of its reports
Excessive urination after Florfenicol + Mometasone + Terbinafine 28 reports · 0.8% of its reports
Excessive urination after Desoxycorticosterone Pivalate 465 reports · 14% of its reports
Excessive urination after Propofol 26 reports · 0.8% of its reports
Excessive urination after Dirlotapide 54 reports · 1.9% of its reports
Excessive urination after Isoflurane 33 reports · 1.2% of its reports

All reported side effects of Tramadol in dogs · Medicines most reported with excessive urination