Blood problems after Polysulfated Glycosaminoglycan in dogs

284 reports to the FDA describe blood problems in dogs given Polysulfated Glycosaminoglycan. That is 5.2% of all reports for this medicine, compared with 1.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

284Reports

62%Marked serious

7.4%Recovered

34%Died or euthanised

24 daysTypical onset

How soon it started

Same day

23 18%

1–2 days

4 3.1%

3–7 days

17 13%

1–4 weeks

28 21%

Over a month

59 45%

How the animals did

Recovered

19 6.7%

Recovered with lasting effects

2 0.7%

Still unwell when reported

72 25%

Died

41 14%

Euthanised

56 20%

Not known

94 33%

Problems reported at the same time

108 38%

98 35%

92 32%

76 27%

68 24%

57 20%

57 20%

39 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

126

12+ years

100

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause blood problems in dogs?: 284 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 24 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood problems with similar medicines

Blood problems after Melarsomine (Immiticide) 513 reports · 2.3% of its reports
Blood problems after Diphenhydramine 267 reports · 5.7% of its reports
Blood problems after Butorphanol 162 reports · 3.6% of its reports
Blood problems after Cefpodoxime 279 reports · 6.9% of its reports
Blood problems after Tramadol 236 reports · 6.3% of its reports
Blood problems after Florfenicol + Mometasone + Terbinafine 39 reports · 1.1% of its reports
Blood problems after Desoxycorticosterone Pivalate 187 reports · 5.6% of its reports
Blood problems after Propofol 106 reports · 3.5% of its reports
Blood problems after Dirlotapide 46 reports · 1.6% of its reports
Blood problems after Isoflurane 101 reports · 3.7% of its reports

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with blood problems