Leucocytosis after Isoflurane in dogs

88 reports to the FDA describe leucocytosis in dogs given Isoflurane. That is 3.2% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

88Reports
70%Marked serious
16%Recovered
36%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
15 20%
1–2 days
22 30%
3–7 days
23 31%
1–4 weeks
9 12%
Over a month
5 6.8%

How the animals did

Recovered
14 16%
Still unwell when reported
29 33%
Died
12 14%
Euthanised
20 23%
Not known
13 15%

Problems reported at the same time

Age of the animals

Under 1 year
7
1–3 years
30
4–7 years
18
8–11 years
31
12+ years
2

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause leucocytosis in dogs?
88 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

All reported side effects of Isoflurane in dogs · Medicines most reported with leucocytosis